M2M2 — Manager II
Manufacturing Operations / Production Supervision (Downstream Processing) Senior Supervisor
Leads the team responsible for downstream processing, ensuring efficient and compliant execution of purification processes. Handles a larger scope than a typical supervisor, possibly overseeing multiple suites or complex processes.
What this level means
Manages an established team or sub-function; owns planning and performance for the group.
- Scope
- An established team or sub-function
- Autonomy
- Owns planning for the group
- Complexity
- Cross-project coordination and priorities
- Impact
- Group delivery and development
- Decision rights
- Owns staffing, priorities, performance for the group
- Leadership
- Manages a team; sometimes manages leads
- Typical experience
- 5–8 yrs
What you'd do
- Supervise and coordinate activities of downstream processing operators.
- Ensure batch processing steps are executed according to SOPs.
- Review and correct manufacturing documentation.
- Lead troubleshooting and continuous improvement initiatives.
- Champion compliance with GMP, GDP, and safety regulations.
- Manage buffer and materials logistics.
- Lead training initiatives for the downstream team.
- Coordinate downstream processing activities.
- Ensure compliance with manufacturing protocols.
- Facilitate team training sessions.
- Oversee logistics for materials and buffers.
- Lead process improvement projects.
Skills, knowledge & tools
- Process supervision
- Documentation review
- Troubleshooting
- Compliance management
- Team leadership
- Logistics management
- Training facilitation
- Quality assurance
- cGMP regulations
- Downstream processing techniques
- Biomanufacturing processes
- Safety protocols
- Logistics and supply chain management
- Training and development
- Process improvement methodologies
- Quality control standards
- Detail-Oriented
- Analytical thinking
- Leadership & Accountability
- Communication
- Calm Under Pressure
- Continuous improvement mindset
- Ethical and Quality-Focused
What good looks like
- Bachelor’s degree in Chemistry, Biochemistry, Chemical Engineering or related discipline.
- 6–10+ years in biomanufacturing or pharmaceutical production.
- 2–5 years in a leadership capacity in downstream processing.
- Experience with tech transfer or scale-up projects.
- ASQ Certified Biotechnology GMP Professional or similar certifications.
Common titles
Manufacturing Operations / Production Supervision (Downstream Processing) Senior Supervisor
Where it sits & what it pays
O*NET / SOC: 13-0000 — Business & Financial Operations Occupations(inferred · under review)
Market-pay benchmarks for this family × level are coming — JobFrame anchors pay to the family/level structure rather than the raw title.